module 5

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Jackie is a 31-year-old pregnant patient (2nd child, two different fathers) single mother of a 6-year-old who is coming for prenatal care since she suspects she is pregnant. She is no longer with the father of Robby, her firstborn. She indicates “pretty serious partying” with the likely father of the baby. By pretty serious partying she means 10-12 drinks per occasion, one to two times per week, plus intermittent methamphetamine use.Which clinical information would be most critical for you to collect in the first visit?What are the greatest risk factors for substance use disorder for this patient?Which harm reduction strategies would you recommend?Identify your city. Then refer this patient to three agencies near you that would support positive health outcomes for this patient.   (These agencies must not have been used in past discussion posts). What was your rationale for choosing these three agencies? 

Week 3 ion channel —3 Peer Response 800w. due9-20-23

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Week 3 ion channel —3 Peer Response 800w. due9-20-23

Instructions:

Please read and respond to the two peers' initial postings for week 2 below. Consider the following questions in your responses.

Compare and contrast your initial posting with those of your peers.  

1. How are they similar or how are they different?

2. What information can you add that would help support the responses of your peers?

3. Ask your peers a question for clarification about their post.

4. What most interests you about their responses? 

5. Summaries at least 1 evidence based article that supports there point.

Please be sure to validate your opinions and ideas with citations and references in APA format.

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Response 1 400 words

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Week 3 Discussion: Ion Channels

Compare and contrast the two different major classes of ion channels.

The two different major classes of ion channels are ligand-gated ion channels and voltage-gated ion channels, both of which are membrane proteins that play a vital role in regulating cell membrane potential and neuron communication (Stahl, 2021). Ligand-gated ion channels are also referred to as ionotropic receptors, this is because LGIC is both a receptor and channel and thus serves a dual function (Stahl, 2021). LGIC are made of amino acids and contain multiple binding sites to bind ligands such as neurotransmitters, ions, and drugs, allowing ions to either bind to a receptor or travel through the channel (Stahl, 2021). Voltage-gated ion channels are channels that mediate nerve conduction, action potential, and neurotransmitter release (Stahl, 2021). These channels are controlled by the change in ionic charge or voltage across the cell membrane (Stahl, 2021). Voltage-gated ion channels tend to be more selective, allowing the influx of only one ion at a time, whereas ligand-gated channels are less selective in nature and allow different types of ions to pass through the channel (Alberts, 2002).

Explain the difference between full agonists, partial agonists, antagonists, and inverse agonists.

An agonist is a ligand that binds to a receptor changing its state to result in a response (Stahl, 2021). The difference between full agonist, partial agonist, antagonist, and inverse agonist is that a full agonist leads to maximum signal transduction, whereas a partial agonist does not reach maximum signal transduction even with full receptor occupancy and can act as an antagonist in the presence of a full agonist (Stahl, 2021). Antagonists, on the other hand, is a ligand that binds to a receptor inhibiting its agonist-stimulated response (Stahl, 2021). Inverse agonists are ligands that when binding to a receptor cause a decrease in signal transduction, thus, their effect is the opposite of an agonist (Stahl, 2021).

References

Alberts, B. (2002). Ion channels and the electrical properties of membranes. Molecular Biology of the Cell – NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK26910/

Stahl, S. M. (2021). Stahl’s Essential Psychopharmacology. https://doi.org/10.1017/9781108975292

Response 2. 400 words

1.
Compare and contrast the two different major classes of ion channels.

To start this discussion board I would like to define what are ion channels. Ion channels are membrane proteins, which play a major role in regulating cellular excitability. There are 3 major ion channels but for this homework assignment, I will compare and contrast voltage-gated ion channels and Ligand-Gated Ion Channels (LGIC).

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Ligand-gated ion channels open when a chemical ligand such as a neurotransmitter binds to the protein (Libretexts, 2023).

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Voltage channels open and close in response to changes in membrane potential (Libretexts, 2023). Ion channels can be classified by how they respond to the environment.

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Ligand-gated ion channel’s permeability is greatly increased when some type of chemical ligand binds to the protein structure (Libretexts, 2023)

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Voltage-gated channels respond to disturbances in cell membrane potential and are highly selective for specific ions such as sodium, potassium, calcium, and chloride (Ratan, 2018).

1.
Explain the difference between full agonists, partial agonists, antagonists, and inverse agonists.


Full agonists


Partial agonist


Antagonist


Inverse agonists

A molecule or chemical compound that can bind to a receptor and activate the receptor therefore causing a biological response (Agonist, partial agonist, antagonist, inverse agonist, 2019)

A molecule or chemical compound that can bind to a receptor and “weakly activate the receptor below maximum response (Agonist, partial agonist, antagonist, inverse agonist, 2019)

A molecule or chemical compound that binds to the receptor but does not cause any activation in the receptor, therefore not causing any biological response (Agonist, partial agonist, antagonist, inverse agonist, 2019)

Molecule of chemical compound that can bind to a receptor leading to deactivation, and decreasing the baseline activity of the receptor (Agonist, partial agonist, antagonist, inverse agonist, 2019)

 

 

 

 

References:

Agonist, partial agonist, antagonist, inverse agonist. PharmaEducation. (2023, August 11). https://pharmaeducation.net/agonist-partial-agonist-antagonist-inverse-agonist/

Libretexts. (2023, January 17). 10.5b: Ion Channels. Medicine LibreTexts. https://med.libretexts.org/Bookshelves/Anatomy_and_Physiology/Anatomy_and_Physiology_(Boundless)/10%3A_Overview_of_the_Nervous_System/10.5%3A_Neurophysiology/10.5B%3A_Ion_Channels

Ratan , N. (2018, October 26). Types of ion channels in the body. News. https://www.news-medical.net/health/Types-of-Ion-Channels-

Weekly Interview Critical Care

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Each week you will take a few minutes and ask 2 people about their personal coping mechanisms for dealing with the stress of working in healthcare during this unique time of Covid. Stress can be physical, emotional, spiritual, or any combination of triggers. Ask a diverse variety of people, don’t forget those in other departs at different points of hierarchy. For example, ask your unit manager, environmental services, volunteers, patients, fellow nurses, etc. Write 2-3 paragraphs on your findings and impressions while respecting the person’s identity.

Impact on World Health due to Disappearing Borders

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Give 2 examples (1 negative, 1 positive) of how you feel the impact the disappearing borders is impacting world health. 

(1 paragraph for each)

Nursing Homework

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Preparing the assignment

1) Follow these guidelines when completing this assignment. Speak with your faculty member if you have questions.

a. Select a scholarly nursing or research article, published within the last five years, related to mental health nursing. The content of the article must relate to evidence-based practice.

· You may need to evaluate several articles to find one that is appropriate.

b. Ensure that no other member of your clinical group chooses the same article, then submit your choice for faculty approval.

c. The submitted assignment should be 2-3 pages in length, excluding the title and reference pages.

2) Include the following sections (detailed criteria listed below and in the Grading Rubric must match exactly).

a. Introduction

· Establishes purpose of the paper

· Captures attention of the reader

b. Article Summary

· Statistics to support significance of the topic to mental health care

· Key points of the article

· Key evidence presented

· Examples of how the evidence can be incorporated into your nursing practice

c. Article Critique

· Present strengths of the article

· Present weaknesses of the article

· Discuss if you would/would not recommend this article to a colleague

d. Conclusion

· Provides analysis or synthesis of information within the body of the text

· Supported by ides presented in the body of the paper

· Is clearly written

e. Article Selection and Approval

· Current (published in last 5 years)

· Relevant to mental health care

· Not used by another student within the clinical group

· Submitted and approved as directed by instructor

f. APA format and Writing Mechanics

1

· Correct use of standard English grammar and sentence structure

· No spelling or typographical errors

· Document includes title and reference pages

· Citations in the text and reference page

dimension

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In this written assignment, identify one specific contemporary issue or trend that you are

interested in learning more about. Choose from the categories below.

• Global Healthcare and Nursing

• Healthcare Reform

• U.S. Healthcare Financing

• Nursing's Role in the U.S. Healthcare System

• Integrative Healthcare

• Nursing Leadership and Management

• Nursing Education

• Nursing Practice

• Nursing Professionalism

• Advancing Nursing as a Profession

• Client Access to Care

• Delivering Client Care

• Interdisciplinary Teamwork and Collaboration

• Ethical Practices in Healthcare

• Quality and Safety in Healthcare Delivery

• Health/Nursing Informatics

In a PowerPoint® presentation (no more than five slides not including the title and reference

slides), include the following information:

• Describe the issue you chose.

• Discuss two significant facts about the issue.

• Support the facts identified with at least one credible source.

• Include the credible source(s) with your PowerPoint®.

I would prefer advancing nursing has a profession

WEEK 7 CASE STUDY MSN5600L

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 Students much review the case study and answer all questions with a scholarly response using APA and include 2 scholarly references. Answer both case studies on the same document .

Attached you can find both case study.

Discussion 7

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Discuss the safety and effectiveness of alternative and complementary medicine for the treatment of specific

illnesses such as cancer, diabetes, and hypertension.  Share your opinions about holistic and allopathic care.

Would have any conflicts or concerns supporting a patient who chooses holistic or allopathic medicine?

Instructions: 

Post your discussion to the Moodle Discussion Forum.  Initial post must be made by Day #3.  Word limit 500 words. Please make sure to provide citations and references (in APA, 7th ed. format) for your work.  

Seach

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 it’s powerpoint presentation
remember to show some of his work like 15-25 photos
remember to a page of 5 sources 

dicussion post sociology

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Respond to two (2) of the following prompts:

  1. How is masculinity described by the authors of our text? Using specific examples, discuss why patriarchal masculinity is not the only form of masculinity. (USLO 5.1, 5.3)
  2. How is sexism explained by the authors of our text? Using specific examples, discuss how society propagates misogyny and objectification of women. (USLO 5.3)
  3. Using one of the three theoretical primary sociological perspectives featured in our text (i.e., functionalism, conflict, and symbolic interactionism) discuss the social construction of gender. Present two tangible examples of how this theory best explains how gender is socially constructed. (USLO 5.4)
  4. Where and how do you get your news? Do you watch network television? Read the newspaper? Go online? How about your parents or grandparents? Do you think it matters where you seek out information? Why, or why not? (USLO 5.5)
  5. How have digital media changed social interactions? Do you believe it has deepened or weakened human connections? Defend your answer. (USLO 5.6)
  6. Do you think technology has truly leveled the world in terms of opportunity? What is your community’s situation in terms of digital inclusion – do you feel there are communities in your region that are struggling to achieve digital inclusion and equity? What are some techniques that we may use to achieve digital equity and inclusion in the U.S.? (USLO 5.7)
  7. In what ways has the Internet and digital apps changed your perception of reality? Explain using a symbolic interactionist, functionalist, and conflict theory perspective. (USLO 5.8)