Global Health 1

MANUSCRIPT PART VI

PLEASE SEE ATTACHED DOCUMENT FOR INSTRUCTIONS AND RUBRIC

2 PAGES

DUE DATE APRIL 10, 2025

NO PLAGIARISM MORE THAN 10 %

SOURCES NO OLDER THAN 5 YEARS WITH IN-TEXT CITATIONS

PLEASE NOTE THAT THIS ASSIGNMENT IS THE FINAL PART OF A PREVIOUS PROJECT, I HAVE UPLOAD HERE PART 1 TO 5 , AND THEN THIS NEW ASSIGNMENT GOING TO BE PART 6 AS A CONTINUATION, AS A SEQUENCE OF THE ASSIGNMENT ATTACHED.

 PLEASE CHECK THE RUBRIC PROFESSOR IS VERY EXIGENT ADN WILL GO POINT BY POINT FOR GRADE THIS ASSIGNMENT. NOTE BOLD LETTER OF THE MANDATORY SECTION THAT NEED TO BE COVER IN THIS SECTION VI.

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Approaches to Disease Management: Dermatologic Disorder

discuss a pediatric dermatologic disorder and its treatment modalities from the perspective of a nurse practitioner. Submission Instructions:

  • Your initial post should be at least 500 words, formatted and cited in current APA style with support from at least 2 academic sources.
  • in paragraph form, no bullet points / numbering.

Weekly Clinical Experience 4

Describe your clinical experience for this week as a nurse practitioner student in a pediatric primary care office.

  • Did you face any challenges, any success? If so, what were they?
  • Describe the assessment of a patient, detailing the signs and symptoms (S&S), assessment, plan of care, and at least 3 possible differential diagnosis with rationales.
  • Mention the health promotion intervention for this patient.
  • What did you learn from this week’s clinical experience that can beneficial for you as an advanced practice nurse?
  • Support your plan of care with the current peer-reviewed research guideline.
  • In paragraph form, no bullet points / numbering. 

Submission Instructions:

  • Your initial post should be at least 500 words, formatted and cited in current APA style with support from at least 2 academic sources published within the last 5 years.

Paraphilia

  Explain the controversy that surrounds your selected disorder-  Pedophilia.

  • Explain your professional beliefs about this disorder, supporting your rationale with at least three scholarly references from the literature.
  • Explain strategies for maintaining the therapeutic relationship with a patient that may present with this disorder.
  • Finally, explain ethical and legal considerations related to this disorder that you need to bring to your practice and why they are important.

2-3 pages including references.No Title

 

  • National Institute for Health and Care Excellence: NICE Guidelines. (2010). Antisocial personality disorder: Prevention and managementLinks to an external site..
    https://www.nice.org.uk/guidance/cg77

  • Boland, R. Verdiun, M. L. & Ruiz, P. (2022).  Kaplan & Sadock’s synopsis of psychiatry (12th ed.). Wolters Kluwer. 
    • Chapter 19 “Personality Disorders”
  • Thapar, A., Pine, D. S., Leckman, J. F., Scott, S., Snowling, M. J., & Taylor, E. A. (Eds.). (2015). Rutter’s child and adolescent psychiatry (6th ed.). Wiley Blackwell.  
    • Chapter 67, “Disorders of Personality”
    • Chapter 68, “Developmental Risk for Psychopathy”
    • Chapter 69, “Gender Dysphoria and Paraphilic Sexual Disorders” (pp. 988–993 only)

Create a Replay for a discussion using APA 7 format, and scholarly references no older than 5 years.

Please ensure that the Reply includes more than 200 words with scholarly articles, and the plagiarism level must remain below 20%.

Typical antipsychotics, also known as first-generation antipsychotics, are medications primarily used in the treatment of schizophrenia and other psychotic disorders. These drugs work by blocking dopamine receptors in the brain, which helps reduce symptoms such as hallucinations, delusions, and agitation (McCuistion et al., 2021). However, due to their mechanism of action, they can also produce a variety of adverse effects, some of which can be serious. Among the most common side effects are extrapyramidal symptoms, which include muscle rigidity, tremors, akathisia, and dystonias. These symptoms can appear shortly after starting treatment and are often a leading cause of treatment noncompliance.

Another important adverse effect is tardive dyskinesia, a neurological disorder characterized by repetitive involuntary movements, especially of the face, tongue, and extremities (Navarro et al., 2024). This effect can appear after prolonged use of typical antipsychotics and, in many cases, is irreversible, making it a particularly worrisome complication. Therefore, periodic monitoring using tools such as the Abnormal Involuntary Movement Scale (AIMS) is essential. Early detection of these symptoms allows for treatment adjustments or consideration of switching to an atypical antipsychotic, which tends to have a lower incidence of these types of effects. Constant clinical monitoring is key to preventing long-term complications.

In addition to motor effects, typical antipsychotics can cause side effects such as sedation, orthostatic hypotension, weight gain, dry mouth, and blurred vision. They can also alter cardiovascular parameters, such as the QT interval on the electrocardiogram, increasing the risk of life-threatening arrhythmias (Rosenthal & Burchum, 2021). In patients with a history of heart disease, these effects can pose a significant risk, so medical evaluations before and during treatment are recommended. It is important for nurses to be trained to identify warning signs and report any clinical changes in the patient. Effective communication among the healthcare team is essential to ensure safe care.

Patient education also plays a fundamental role in managing the adverse effects of antipsychotics. Nursing professionals should inform patients and their families about potential side effects and how to recognize them, as well as the importance of not discontinuing treatment without consulting a physician (Navarro et al., 2024). Furthermore, they should promote strategies to minimize risks, such as maintaining good hydration, avoiding alcohol consumption, and complying with clinical follow-ups. Patient empowerment through education improves therapeutic adherence and reduces the likelihood of complications. An informed patient is better able to make informed decisions about their health.

Finally, it is essential to adopt an individualized therapeutic approach, considering the patient’s medical history, comorbid conditions, and tolerance to the medication. Not all patients respond equally to the same drugs, so adjusting the dose or changing medications may be necessary. Nursing professionals should work with the medical team to design patient-centered care plans that balance the benefits of treatment with minimizing its adverse effects. This comprehensive approach allows for safer, more humane, and more effective care. In short, a thorough understanding of the adverse effects of typical antipsychotics is essential to optimizing treatment and ensuring the well-being of psychiatric patients.  

References:

McCuistion, L. E., Vuljoin-DiMaggio, K., Winton, M. B., & Yeager, J. J. (2021). Pharmacology. A Patient-Centered Nursing Process Approach (11th Ed.). Elsevier.

Navarro, V. D., Navarro, M. T., Negre, E., Negre, C., Navarro, A. B., & Dalda, J. Á. (2024). Detection of sexual dysfunctions associated with the use of antipsychotics and antidepressants. Health Research Journal, 5(2), 2660-7085. https://dialnet.unirioja.es/servlet/articulo?codigo=9335621

Rosenthal, L. D., & Burchum, J. (2021). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd Ed.). Elsevier.

Create a Reply for a discussion using APA 7 format, and scholarly references no older than 5 years.

Please ensure that the Reply includes more than 200 words with scholarly articles, and the plagiarism level must remain below 20%.

Antipsychotics: Common Adverse Effects and Safety Implications in the Clinical Setting

Antipsychotic drugs, especially first-generation or typical antipsychotics, have been relevant to the treatment of psychiatric disorders including schizophrenia for many years. Though effective at alleviating positive symptoms — like hallucinations and delusions — their use is often marred by a wide variety of adverse effects. Being aware of these effects is essential to advanced practice providers who are providing safe, patient-centered care. The primary mechanism of action of typical antipsychotics is dopamine D2 receptor antagonism, which accounts for both the therapeutic and adverse effects of the medications (Rosenthal & Burchum, 2021).
Extrapyramidal symptoms (EPS) are among the most common and well-established adverse effects of typical antipsychotics. They include acute dystonia, parkinsonism, akathisia, and tardive dyskinesia (Rosenthal & Burchum, 2021). Acute dystonia, characterized by sustained involuntary muscle contractions, and parkinsonism, characterized by rigidity and bradykinesia, usually develop in the first few days to weeks of treatment. A side effect of long-term use is tardive dyskinesia, which is usually irreversible, and is marked by abnormal, involuntary muscle movements, primarily of the tongue, face (Muench & Hamer, 2020). Well understood, the risk of EPS necessitates routine monitoring and prompt identification, with agents such as benztropine or diphenhydramine for symptomatic control.
A second problem with typical antipsychotics is neuroleptic malignant syndrome (NMS), a rare, but life-threatening, condition characterized by hyperthermia, muscle rigidity, altered mental status, and autonomic instability. According to Rosenthal and Burchum (2021), whether or not to intervene, and the need for supportive care in the meantime, are vital to preventing serious sequela.

Cardiovascular effects, such as orthostatic hypotension and QT prolongation, are other important risks associated with antipsychotic medications, especially with haloperidol and chlorpromazine (Rosenthal & Burchum, 2021). These effects require baseline and ongoing ECG monitoring in at-risk populations. Moreover, anticholinergic side effects, including dry mouth, constipation, urinary retention, and blurred vision are known to interfere with adherence and quality of life[1, 2].
On top of these risks, individualising treatment is important. Medication selection should be guided by the patient-specific factors (age, comorbidities, and prior response to treatments). Additionally, patient education has a key function in enhancing adherences and surveying early signs of negative consequences. Educating patients regarding the need to report muscle stiffness, abnormal movements, or sudden fever will prevent Journal of Advanced Nursing 5 complications, and help achieve better therapeutic outcomes (Muench & Hamer, 2020; Correll et al., 2021).
To wrap this up, the usual antipsychotics are still an obligatory device in the psychiatric seat, however there should be a trade-off between the utilization of the earlier. Preventive measures through active and continuous vigilance, individualized healthcare provision, and educating the patient to secure the best outcome while ensuring safety should be taken into consideration.

References

Correll, C. U., Solmi, M., Croatto, G., Schneider, L., Rohani-Montez, S. C., Fairley, L., & Kishimoto, T. (2021). Mortality risk associated with antipsychotic drug use in children and young people: A systematic review and meta-analysis of observational studies. JAMA Psychiatry, 78(5), 519–530. https://doi.org/10.1001/jamapsychiatry.2021.0030

Muench, J., & Hamer, A. M. (2020). Adverse effects of antipsychotic medications. American Family Physician, 101(3), 169–177. Retrieved from https://www.aafp.org/pubs/afp/issues/2020/0201/p169.html

Rosenthal, L. D., & Burchum, J. R. (2021). Lehne’s pharmacotherapeutics for advanced practice providers (2nd ed.). Elsevie